Insulin and hypokalemia relationship

Insulin and Potassium | Diabetes Library

insulin and hypokalemia relationship

Impaired renal function, potassium-sparing drugs, hypertonicity and insulin . Although rare, the inverse etiological relation between hyponatremia and DM also. Insulin is a key player in the control of intermediary metabolism, and the big picture is that it . Insulin also increases the permiability of many cells to potassium. EFFECTS ON INSULIN: Insulin is a potent stimulus for hypokalaemia, sparing body potassium from urinary excretion by transporting it into cells. Potassium also .

Otherwise, there's no reason that someone with hyperkalemia due to extracellular shifts, say from acidosis ie. Feb 4, '11 Joined: I found this site looking for more informaiton abotu my OWN issus as I have been on mEq potasisum for abotu2 years now and just had t raise my insulin a litle and now I am feeling the old low potassium symptoms again.

It starts as muscle oain and fluid retention, so common in Diabetics I have to wonder how many on insulin need potassium and do not know it. My serum K was 4. I also had 15 years chronic IBS that stopped like turning off a faucet when i started supplementing 40mEq potassium.

Potassium as a link between insulin and the renin-angiotensin-aldosterone system.

Hip pain I though was arthritis gone, back pain, same. Urinary leakage I thought was due to early hysterectomy, gone.

insulin and hypokalemia relationship

Pleases become pioneers with Diabetics in running this test. Feb 7, '11 Occupation: Red blood cell are part of the extracellular fluid so I don't understand your point Valharly. The serum and red blood cells are all part of blood and are extracellular not intracellular.

This is the most common cause of hypokalemia. Other causes of hypokalemia include: Increased excretion or loss of potassium from your body.

Insulin & Potassium

Some medications may cause potassium loss which can lead to hypokalemia. Common medications include loop diuretics such as Furosemide. Other drugs include steroids, licorice, sometimes aspirin, and certain antibiotics.

Your kidneys will excrete too much potassium.

Potassium and Insulin Relationship | allnurses

You may have hypokalemia from a loss of body fluids due to excessive vomiting, diarrhea, or sweating. Endocrine or hormonal problems such as increased aldosterone levels - aldosterone is a hormone that regulates potassium levels. Certain diseases of the endocrine system, such as Aldosteronism, or Cushing's syndrome, may cause potassium loss. Poor dietary intake of potassium Symptoms of Hypokalemia: You may not have any symptoms unless your blood potassium levels are significantly lowered.

You may have muscle weakness, fatigue, or cramps.

Physiologic Effects of Insulin

On exam, your healthcare provider may notice your reflexes to be lessened. Follow your healthcare provider's instructions regarding raising your blood potassium level. Some had type 2 diabetes, while others were normal. Only those diabetics that required insulin or were treated with thiazolidinediones were excluded from the study.

insulin and hypokalemia relationship

Each diabetic patient was treated with either metformin, a sulfonyl urea medication, or a combination of the two. They all ate a specific diet for 8 days and, prior to being tested, drank cc of water at bedtime the night before the test.

On the ninth day, the participants were fasting and underwent a test involving the infusion of insulin for two hours. After the insulin was started, each participant was also given IV glucose within 4 minutes of starting the insulin in order to keep the glucose levels as stable as possible. The plasma insulin level was checked along with the levels of potassium and glucose at the beginning and the end of the insulin in fusion.

The researchers were looking at how much the potassium fell when the participants were given both glucose and insulin for two hours.

insulin and hypokalemia relationship

They also measured the amount of phosphate in the bloodstream before and after the 2-hour test. The diabetic participants had higher glucose levels as well. The levels of creatinine, phosphate, and potassium were the same in both groups. At the end of the study, type 2 diabetics had more insulin resistance when compared to the normal participants.

insulin and hypokalemia relationship

The more the diabetic person weighed, the greater was their level of insulin resistance. Potassium and phosphate levels, however, were not related to the weight of the participant.

Both the diabetics and nondiabetics had a reduction in potassium when insulin and glucose were given. There appeared to be no relationship between the insulin resistance and the fall in potassium and phosphate levels, however.