Relationship between weight and longevity

Optimal body weight for health and longevity: bridging basic, clinical, and population research

relationship between weight and longevity

[] The relationships between weight and mortality are different for older adults. “Years of life” (YOL) was defined as the life expectancy from age 65 to death. Keywords: Obesity, Longevity, Lifestyle, Mortality, Morbidity, Life expectancy, .. Medicine (Al-Soufi ) investigated the association between body weight and. The relationship between adult body weight and health in human is of between maximum mature weight and maximum longevity (18).

Fat may have a protective effect. Our bodies use fat for energy storage. In the process of fighting a disease we need energy. In people that have more energy stores that may have the ability to overcome a significant body insult from an acute or chronic disease.

For example, an acute disease such as pneumonia or a chronic disease such as heart failure or emphysema. More importantly, I think there is more to daily health than weight and the pursuit of being underweight.

relationship between weight and longevity

In this regard, fitness is more than being thin and is more important than being thin. Given the obesity paradox, I asked Dr.

Extra Weight Linked To Longevity | HuffPost Life

Lopez-Jimenez how he counsels patients regarding weight loss. I believe this is very important advice. In the United States we are facing an obesity epidemic. A lot of this is driven by lifestyles that are less active and food sources that are calorie dense.

Healthy food choices can augment fitness and enhance muscle mass retention. Trying to maintain a healthy weight for your body frame still remains important and a fundament aspect the long-term health.

Dangers of Being Underweight Finally, I really want to emphasize that being underweight is also significant risk factor. This may be due to lack of muscle mass or lack of energy reserve to fight acute and chronic diseases.

Optimal body weight for health and longevity: bridging basic, clinical, and population research

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In a recent meta-analysis of 97 prospective cohort studies 2. These large studies generally benefited from sufficient statistical power to allow for the analysis of finer BMI categories, and therefore had no reason to use such broad categories.

In most of these omitted studies, the BMI range associated with the lowest mortality was around Second, the meta-analysis included numerous studies conducted among elderly or sick populations as well as current and past smokers.

In particular, the broad reference group BMI Because the overweight and obese groups were compared with this heterogeneous group, the associations with the higher-BMI groups were seriously underestimated, creating an artifact of reduced mortality among the overweight and moderately obese groups Willett et al. Weight loss can result from the direct effects of chronic disease on weight or from conscious efforts motivated by a diagnosis of serious illness.

Many conditions that cause weight loss, such as chronic obstructive pulmonary disease, depression, and neurodegenerative diseases, may remain undiagnosed for years. To minimize the impact of reverse causation, it is important to exclude patients with existing chronic diseases at baseline Hu, The use, distribution or reproduction in other forums is permitted, provided the original author s or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.

No use, distribution or reproduction is permitted which does not comply with these terms. This article has been cited by other articles in PMC. Abstract Total caloric restriction CR without malnutrition is a well-established experimental approach to extend life span in laboratory animals.

Although CR in humans is capable of shifting several endocrinological parameters, it is not clear where the minimum inflection point of the U-shaped curve linking body mass index BMI with all-cause mortality lies.

The exact trend of this curve, when used for planning preventive strategies for public health is of extreme importance.

relationship between weight and longevity

Normal BMI ranges from Other studies show that the lowest mortality in the entire range of BMI is obtained in the overweight range 25—